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KMID : 0383820090670030234
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Tuberculosis and Respiratory Diseases
2009 Volume.67 No. 3 p.234 ~ p.238
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A Case of Henoch-Schonlein Purpura Developed during Treatment of Lung Cancer
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Kang Min-Soo
Noh Geum-Yeub
Jang Young-Joo
Cho Soo-Youn
Lim Gyung-Jin
Noh Hee-Seon
Kim Hye-Ryoun
Kim Cheol-Hyeon
Lee Jae-Cheol
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Abstract
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Henoch-Schonlein Purpura (HSP) is a systemic vasculitis involving small vessels with the deposition of immune complexes containing IgA and C3, which is characterized by associated skin, joint, renal, and gastrointestinal manifestations. Although there were several causes such as autoimmunity, infection, and drugs, it also can be presented as a form of vasculitidies associated with malignancies. We report a case of HSP developed during treatment for non-small cell lung cancer in a 66-year-old man. Multiple purpuric skin lesions occurred in both legs after the first cycle of chemotherapy, which was diagnosed as HSP by clinical and pathologic examinations. Due to the itching sensation, topical steroid was applied and the patient was improved 3 weeks later without a scheduled change in chemotherapy.
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KEYWORD
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Lung neoplasms, Henoch-Schonlein purpura, Vasculitis
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